Cancer cells have epigenetic alterations that are known to drive cancer progression. The
reversibility of the epigenetic posttranslational modifications on chromatin and DNA renders
targeting these modifications an attractive means for cancer therapy. Cellular epigenetic
status interacts with cell metabolism, and we are now beginning to understand the nature of
how this interaction occurs and the biological contexts that mediate its function. Given the
tremendous interest in understanding and targeting metabolic reprogramming in cancer, this …