Clinical performance of the Elecsys electrochemiluminescent immunoassay for the detection of SARS-CoV-2 total antibodies
J Favresse, C Eucher, M Elsen, M Tré-Hardy… - Clinical …, 2020 - academic.oup.com
Clinical chemistry, 2020•academic.oup.com
ROC curve cutoff (ie,> 0.165) had no effect on the measured diagnostic specificity (Fig. 1).
The optimal ROC cutoff showed excellent clinical performance 14 days after RT-PCR
positivity or the onset of COVID-19 symptoms. Additional studies are needed to confirm the
best cutoff. Expert societies are urged to provide guidance on the best time after RTPCR
positivity or symptom onset to perform serological investigations, which are important
determinants of the true positivity rate.
The optimal ROC cutoff showed excellent clinical performance 14 days after RT-PCR
positivity or the onset of COVID-19 symptoms. Additional studies are needed to confirm the
best cutoff. Expert societies are urged to provide guidance on the best time after RTPCR
positivity or symptom onset to perform serological investigations, which are important
determinants of the true positivity rate.
ROC curve cutoff (ie,> 0.165) had no effect on the measured diagnostic specificity (Fig. 1). The optimal ROC cutoff showed excellent clinical performance 14 days after RT-PCR positivity or the onset of COVID-19 symptoms. Additional studies are needed to confirm the best cutoff. Expert societies are urged to provide guidance on the best time after RTPCR positivity or symptom onset to perform serological investigations, which are important determinants of the true positivity rate.
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