[HTML][HTML] Analysis of type I IFN response and T cell activation in severe COVID-19/HIV-1 coinfection: A case report

G d'Ettorre, G Recchia, M Ridolfi, G Siccardi… - Medicine, 2020 - journals.lww.com
Interventions: SARS-CoV-2/HIV-1-coinfected female patient under darunavir/cobicistat
regimen received a 7-days hydroxychloroquine therapy. Analysis of IFNα/β mRNA levels
and CD4 and CD8 T cell (CD38, human leukocyte antigen-DR [HLA-DR], CD38 HLA-DR)
frequencies were performed by RT/real-time PCR assays and flow cytometry, respectively.
Median relative difference (MRD) was calculated for each immunological variable. For
values greater than reference, MRD should be a positive number and for values that are …