Gastric inhibitory polypeptide enhancement of the insulin effect on fatty acid incorporation into adipose tissue in the rat
B Beck, JP Max - Regulatory peptides, 1983 - Elsevier
The influence of gastric inhibitory polypeptide (GIP) on fatty acid incorporation into adipose
tissue (FIAT) was studied in the rat on epididymal fat pads at concentrations amounting to 1,
2 and 4 ng/ml. Without insulin in the incubation medium, GIP induced a slight though
significant FIAT decrease with a maximum of 9% for 2 ng/ml concentration. In the presence
of rat insulin (100 μU/ml), it significantly enhanced the insulin-induced FIAT increase, that
progressed from 106.4% of the basal value to 110.5% for 1 ng/ml concentration (P< 0.025) …
tissue (FIAT) was studied in the rat on epididymal fat pads at concentrations amounting to 1,
2 and 4 ng/ml. Without insulin in the incubation medium, GIP induced a slight though
significant FIAT decrease with a maximum of 9% for 2 ng/ml concentration. In the presence
of rat insulin (100 μU/ml), it significantly enhanced the insulin-induced FIAT increase, that
progressed from 106.4% of the basal value to 110.5% for 1 ng/ml concentration (P< 0.025) …
