Effects of weight regain following intentional weight loss on glucoregulatory function in overweight and obese adults with pre-diabetes
KM Beavers, LD Case, CS Blackwell, JA Katula… - Obesity research & …, 2015 - Elsevier
Objective To assess the extent to which initial, intentional weight loss-associated
improvements in glucose tolerance and insulin action are diminished with weight regain.
Methods 138 overweight and obese (BMI: 32.4±3.9 kg/m 2), adults (59.0±9.7 years), with pre-
diabetes were followed through a 6-month weight loss intervention and subsequent 18-
month weight maintenance period, or usual care control condition. Longitudinal change in
weight (baseline, 6, 24 months) was used to classify individuals into weight pattern …
improvements in glucose tolerance and insulin action are diminished with weight regain.
Methods 138 overweight and obese (BMI: 32.4±3.9 kg/m 2), adults (59.0±9.7 years), with pre-
diabetes were followed through a 6-month weight loss intervention and subsequent 18-
month weight maintenance period, or usual care control condition. Longitudinal change in
weight (baseline, 6, 24 months) was used to classify individuals into weight pattern …