Adult hippocampal neurogenesis is regulated by the microbiome
ES Ogbonnaya, G Clarke… - Biological …, 2015 - biologicalpsychiatryjournal.com
Accumulating evidence suggests that the microbiota plays a key role in the brain and
behavior (1–4). Alterations in the gut microbiota-brain axis have been implicated in stress-
related disorders such as depression and anxiety, in neurodevelopmental disorders such as
autism, and in cognitive functioning (1, 4–6). Neurogenesis, the birth of new neurons, in the
adult hippocampus is thought to play an important role in learning and memory and
responses to stress and antidepressant drugs (7–9). Germ-free (GF) mice have grown up …
behavior (1–4). Alterations in the gut microbiota-brain axis have been implicated in stress-
related disorders such as depression and anxiety, in neurodevelopmental disorders such as
autism, and in cognitive functioning (1, 4–6). Neurogenesis, the birth of new neurons, in the
adult hippocampus is thought to play an important role in learning and memory and
responses to stress and antidepressant drugs (7–9). Germ-free (GF) mice have grown up …