Protein abundance and phosphorylation convey important information about pathway
activity and molecular pathophysiology in diseases including cancer, providing biological
insight, informing drug and diagnostic development, and guiding therapeutic intervention.
Analyzed tissues are usually collected without tight regulation or documentation of ischemic
time. To evaluate the impact of ischemia, we collected human ovarian tumor and breast
cancer xenograft tissue without vascular interruption and performed quantitative proteomics …