Role of Intercellular Adhesion Molecule–1 and Lymphocyte Function-Associated Antigen–1 During Nonsuppurative Destructive Cholangitis in A Mouse Graft–Versus …
CD Howell, J Li, W Chen - Hepatology, 1999 - journals.lww.com
Abstract Intercellular adhesion molecule–1 (ICAM–1) is expressed abnormally on the bile
duct epithelium during the course of primary biliary cirrhosis (PBC), but the importance of
ICAM–1 and its lymphocyte function–associated antigen–1 (LFA–1) receptor during the
course of nonsuppurative destructive cholangitis (NSDC) has not been defined. To address
this question, we defined the relationship between ICAM–1 on the intrahepatic bile duct
epithelium and the evolution of NSDC lesions in a mouse graft–versus–host disease …
duct epithelium during the course of primary biliary cirrhosis (PBC), but the importance of
ICAM–1 and its lymphocyte function–associated antigen–1 (LFA–1) receptor during the
course of nonsuppurative destructive cholangitis (NSDC) has not been defined. To address
this question, we defined the relationship between ICAM–1 on the intrahepatic bile duct
epithelium and the evolution of NSDC lesions in a mouse graft–versus–host disease …