Purification and biophysical characterization of hepatitis B antigen
CY Kim, JG Tilles - The Journal of Clinical Investigation, 1973 - Am Soc Clin Investig
CY Kim, JG Tilles
The Journal of Clinical Investigation, 1973•Am Soc Clin InvestigHepatitis B antigen (HB Ag) has been purified from serum by pepsin digestion and
equilibrium sedimentation. The sedimentation coefficient, density, particle size, and
electrophoretic mobility have been determined before and after purification and found to be
unaltered. In addition, the diffusion constant and molecular weight of purified HB Ag have
been documented. Because the biophysical characteristics found are not consistant with
those of any known virus, it is believed that native HB Ag is made up almost entirely of …
equilibrium sedimentation. The sedimentation coefficient, density, particle size, and
electrophoretic mobility have been determined before and after purification and found to be
unaltered. In addition, the diffusion constant and molecular weight of purified HB Ag have
been documented. Because the biophysical characteristics found are not consistant with
those of any known virus, it is believed that native HB Ag is made up almost entirely of …
Hepatitis B antigen (HB Ag) has been purified from serum by pepsin digestion and equilibrium sedimentation. The sedimentation coefficient, density, particle size, and electrophoretic mobility have been determined before and after purification and found to be unaltered. In addition, the diffusion constant and molecular weight of purified HB Ag have been documented.
Because the biophysical characteristics found are not consistant with those of any known virus, it is believed that native HB Ag is made up almost entirely of incomplete virus.
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