Publisher Summary This chapter describes the scar reduction mechanism mediated by
astroglia by comparing the behavior of highly purified populations of immature vs. mature
astrocytes, when transferred on Millipore filters into the brains of adult rodents. Immature
astrocytes, which are enriched in culture for four days and seeded onto nitro-cellulose, can
reduce scar formation when implanted into P60 acallosal mice. However, cultured astrocytes
are somewhat less effective in reducing scar formation than their direct donor to host …