[HTML][HTML] Characteristics of pediatric SARS-CoV-2 infection and potential evidence for persistent fecal viral shedding

Y Xu, X Li, B Zhu, H Liang, C Fang, Y Gong, Q Guo… - Nature medicine, 2020 - nature.com
Y Xu, X Li, B Zhu, H Liang, C Fang, Y Gong, Q Guo, X Sun, D Zhao, J Shen, H Zhang, H Liu…
Nature medicine, 2020nature.com
We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection
cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA.
Symptoms in these cases were nonspecific and no children required respiratory support or
intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the
infection in adult cases. Notably, eight children persistently tested positive on rectal swabs
even after nasopharyngeal testing was negative, raising the possibility of fecal–oral …
Abstract
We report epidemiological and clinical investigations on ten pediatric SARS-CoV-2 infection cases confirmed by real-time reverse transcription PCR assay of SARS-CoV-2 RNA. Symptoms in these cases were nonspecific and no children required respiratory support or intensive care. Chest X-rays lacked definite signs of pneumonia, a defining feature of the infection in adult cases. Notably, eight children persistently tested positive on rectal swabs even after nasopharyngeal testing was negative, raising the possibility of fecal–oral transmission.
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