Understanding the connection between platelet-activating factor, a UV-induced lipid mediator of inflammation, immune suppression and skin cancer
E Damiani, SE Ullrich - Progress in lipid research, 2016 - Elsevier
Lipid mediators of inflammation play important roles in several diseases including skin
cancer, the most prevalent type of cancer found in the industrialized world. Ultraviolet (UV)
radiation is a complete carcinogen and is the primary cause of skin cancer. UV radiation is
also a potent immunosuppressive agent, and UV-induced immunosuppression is a well-
known risk factor for skin cancer induction. An essential mediator in this process is the
glyercophosphocholine 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine commonly referred to …
cancer, the most prevalent type of cancer found in the industrialized world. Ultraviolet (UV)
radiation is a complete carcinogen and is the primary cause of skin cancer. UV radiation is
also a potent immunosuppressive agent, and UV-induced immunosuppression is a well-
known risk factor for skin cancer induction. An essential mediator in this process is the
glyercophosphocholine 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine commonly referred to …