Vagal afferent fibers almost exclusively innervate islets in the rat pancreas as demonstrated by anterograde tracing
WL Neuhuber - Journal of the autonomic nervous system, 1989 - Elsevier
Anterograde tracing from the nodose ganglion with wheat germ agglutinin-horseradish
peroxidase conjugate (WGA-HRP) was utilized to investigate vagal afferent innervation of
the rat pancreas. Labelled afferent fibers were consistently detected in islets in all animals.
Only about 10% of islets were labelled even in best cases. In only 5 out of 16 rats, acini and
excretory ducts received afferent innervation. Injections into the right nodose ganglion
resulted in labelling preferentially within the splenic lobe, whereas injections into the left …
peroxidase conjugate (WGA-HRP) was utilized to investigate vagal afferent innervation of
the rat pancreas. Labelled afferent fibers were consistently detected in islets in all animals.
Only about 10% of islets were labelled even in best cases. In only 5 out of 16 rats, acini and
excretory ducts received afferent innervation. Injections into the right nodose ganglion
resulted in labelling preferentially within the splenic lobe, whereas injections into the left …