Effect of reversible intermittent intra-abdominal vagal nerve blockade on morbid obesity: the ReCharge randomized clinical trial
S Ikramuddin, RP Blackstone, A Brancatisano, J Toouli… - Jama, 2014 - jamanetwork.com
Importance Although conventional bariatric surgery results in weight loss, it does so with
potential short-term and long-term morbidity. Objective To evaluate the effectiveness and
safety of intermittent, reversible vagal nerve blockade therapy for obesity treatment. Design,
Setting, and Participants A randomized, double-blind, sham-controlled clinical trial involving
239 participants who had a body mass index of 40 to 45 or 35 to 40 and 1 or more obesity-
related condition was conducted at 10 sites in the United States and Australia between May …
potential short-term and long-term morbidity. Objective To evaluate the effectiveness and
safety of intermittent, reversible vagal nerve blockade therapy for obesity treatment. Design,
Setting, and Participants A randomized, double-blind, sham-controlled clinical trial involving
239 participants who had a body mass index of 40 to 45 or 35 to 40 and 1 or more obesity-
related condition was conducted at 10 sites in the United States and Australia between May …