Standard cell culture models have been used to investigate disease pathology and to test
new therapies for over fifty years. However, these model systems have often failed to mimic
the changes occurring within three-dimensional (3-D) space where pathology occurs in vivo.
To truthfully represent this, an emerging paradigm in biology is the importance of modelling
disease in a physiologically relevant 3-D environment. One of the approaches for 3-D cell
culture is bioelectrospray technology. This technique uses an alginate-based 3-D …