Pathologic and immunologic alterations in early stages of beryllium disease

LS Newman, K Kreiss, TE King Jr, S Seay… - Am Rev Respir …, 1989 - atsjournals.org
LS Newman, K Kreiss, TE King Jr, S Seay, PA Campbell
Am Rev Respir Dis, 1989atsjournals.org
Beryllium lung disease is a chronic granulomatous disorder in which a beryllium-specific
immune response plays a central role. By using a measure of cellular immune response to
beryllium salts, bronchoalveolar lavage (BAL), and lung biopsy, we have identified 12 new
cases of beryllium disease. Each of these individuals had pathologic changes on biopsy,
lymphocytic alveolitls on
Summary
Beryllium lung disease is a chronic granulomatous disorder in which a beryllium-specific immune response plays a central role. By using a measure of cellular immune response to beryllium salts, bronchoalveolar lavage (BAL), and lung biopsy, we have identified 12 new cases of beryllium disease. Each of these individuals had pathologic changes on biopsy, lymphocytic alveolitls on
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