Absolute lymphocyte count predicts abscopal responses and outcomes in patients receiving combined immunotherapy and radiation therapy: analysis of 3 phase 1/2 …

D Chen, V Verma, RR Patel, HB Barsoumian… - International Journal of …, 2020 - Elsevier
Purpose Research to elucidate predictive factors of the abscopal effect is an essential first
step toward potentially modifying these factors to increase the incidence of systemic
antitumor effects. This study, using data from 3 institutional phase 1/2 trials, examined the
predictive capacity of recorded parameters in patients undergoing combined radiation
therapy (RT) and immunotherapy and explored outcomes based on those predictive factors.
Methods and Materials All patients underwent combined immunotherapy and RT and had at …