Hepatitis B virus infection, its sequelae, and prevention by vaccination
LM Huang, CY Lu, DS Chen - Current opinion in immunology, 2011 - Elsevier
LM Huang, CY Lu, DS Chen
Current opinion in immunology, 2011•ElsevierHepatitis B virus (HBV) infection is a global health problem. There are> 350 million of people
chronically infected with this virus worldwide. Hepatitis B vaccines are effective in preventing
the infection. Humoral immunity is the key factor in conferring the protection. Hepatitis B
surface antibody titers of≥ 10mIU/mL are protective. Chronic carriage of HBV is related to
the age when the infection occurs, the younger the age the higher the chronicity rate. Hence,
vaccination should be given in early childhood. People vaccinated in infancy have a …
chronically infected with this virus worldwide. Hepatitis B vaccines are effective in preventing
the infection. Humoral immunity is the key factor in conferring the protection. Hepatitis B
surface antibody titers of≥ 10mIU/mL are protective. Chronic carriage of HBV is related to
the age when the infection occurs, the younger the age the higher the chronicity rate. Hence,
vaccination should be given in early childhood. People vaccinated in infancy have a …
Hepatitis B virus (HBV) infection is a global health problem. There are >350 million of people chronically infected with this virus worldwide. Hepatitis B vaccines are effective in preventing the infection. Humoral immunity is the key factor in conferring the protection. Hepatitis B surface antibody titers of ≥10mIU/mL are protective. Chronic carriage of HBV is related to the age when the infection occurs, the younger the age the higher the chronicity rate. Hence, vaccination should be given in early childhood. People vaccinated in infancy have a protection of >20 years, and hepatocellular carcinoma decreases in them. Although the vaccine-conferred immunity wanes by time, a universal booster is not recommended at present.
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