Efficacy and safety of recombinant hepatitis B vaccine in infants born to HBsAg-positive mothers
EK Yeoh, WK Chang, P Ip, KH Chan, E Chan, C Fung - Journal of Infection, 1986 - Elsevier
Infants born to HBsAg-positive women were randomly assigned to receive either the plasma-
derived hepatitis B vaccine or the yeast-derived recombinant hepatitis B vaccine within 12 h
of birth, simultaneously with HBIg. The second and third doses of both vaccines were given
at 1 and 6 months of age respectively. Two hundred and twenty-two infants received two
doses, and 80 infants received three doses of either vaccine. Five infants were found to be
HBsAg-positive at 6 months of age. Four of these infants had received the plasma vaccine …
derived hepatitis B vaccine or the yeast-derived recombinant hepatitis B vaccine within 12 h
of birth, simultaneously with HBIg. The second and third doses of both vaccines were given
at 1 and 6 months of age respectively. Two hundred and twenty-two infants received two
doses, and 80 infants received three doses of either vaccine. Five infants were found to be
HBsAg-positive at 6 months of age. Four of these infants had received the plasma vaccine …