Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease

O Skog, S Korsgren, Å Melhus… - Current Opinion in …, 2013 - journals.lww.com
O Skog, S Korsgren, Å Melhus, O Korsgren
Current Opinion in Endocrinology, Diabetes and Obesity, 2013journals.lww.com
In humans there is limited support for T1D being primarily an autoimmune disease; instead
available findings support the view that T1D can be regarded as an innate inflammatory
disease affecting the entire pancreas, but with its main clinical manifestations emanating
from the loss of the insulin-producing cells.
Summary
In humans there is limited support for T1D being primarily an autoimmune disease; instead available findings support the view that T1D can be regarded as an innate inflammatory disease affecting the entire pancreas, but with its main clinical manifestations emanating from the loss of the insulin-producing cells.
Lippincott Williams & Wilkins