[HTML][HTML] Scapinin, a putative protein phosphatase-1 regulatory subunit associated with the nuclear nonchromatin structure
J Sagara, T Higuchi, Y Hattori, M Moriya… - Journal of Biological …, 2003 - ASBMB
It is thought that the nuclear nonchromatin structures, such as the nuclear matrix and lamina,
play regulatory roles in gene expression. In this study, we identified an insoluble protein that
was associated with the chromatin-depleted nuclear structure of proliferating human
leukemia HL-60 cells. Preparation of the chromatin-depleted nuclear structure, referred to as
the nuclear matrix-intermediate filament scaffold (Fey, E., Krochmalnic, G., and Penman,
S.(1986) J. Cell. Biol. 102, 1654–1665), involved cell extraction using a series of buffers …
play regulatory roles in gene expression. In this study, we identified an insoluble protein that
was associated with the chromatin-depleted nuclear structure of proliferating human
leukemia HL-60 cells. Preparation of the chromatin-depleted nuclear structure, referred to as
the nuclear matrix-intermediate filament scaffold (Fey, E., Krochmalnic, G., and Penman,
S.(1986) J. Cell. Biol. 102, 1654–1665), involved cell extraction using a series of buffers …