Endocrine and metabolic effects of experimental obesity in man

EAH Sims, E Danforth Jr, ES Horton, GA Bray… - Proceedings of the 1972 …, 1973 - Elsevier
Publisher Summary This chapter discusses the endocrine and metabolic effects of the
experimental obesity in humans. All the changes witnessed in spontaneous obesity except
for the increase in adipocyte number have been reproduced in experimental obesity. It has
been found that endocrine and metabolic changes are associated with gain in weight.
Normal subjects fattened by eating a mixed diet require more calories in relation to their
body surface area for maintenance of the obese state than they require when at their natural …