Incidence of skin cancer after renal transplantation in The Netherlands

MM HARTEVELT, JANNB BAVINCK… - …, 1990 - journals.lww.com
MM HARTEVELT, JANNB BAVINCK, AMM KOOTTE, BJ VERMEER…
Transplantation, 1990journals.lww.com
The incidence of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) was
analyzed separately in all 764 patients who received a renal allograft between 1966 and
1988 at the Leiden University Hospital. The mean follow-up period was 8.7 posttransplant
years (range 1—21 years). During this time period 176 skin cancers were diagnosed in 47
patients. The overall risk to develop a first tumor increased from 10% after 10 years to 40%
after 20 years of graft survival. The overall incidence of SCC was 250 times higher and that …
Abstract
The incidence of squamous cell carcinoma (SCC) and basal cell carcinoma (BCC) was analyzed separately in all 764 patients who received a renal allograft between 1966 and 1988 at the Leiden University Hospital. The mean follow-up period was 8.7 posttransplant years (range 1—21 years). During this time period 176 skin cancers were diagnosed in 47 patients. The overall risk to develop a first tumor increased from 10% after 10 years to 40% after 20 years of graft survival. The overall incidence of SCC was 250 times higher and that of BCC 10 times higher when compared with the general Dutch population. Moreover the localization of SCCs and BCCs differed considerably.
Lippincott Williams & Wilkins