Exploration of the sialic acid world
R Schauer, JP Kamerling - Advances in carbohydrate chemistry and …, 2018 - Elsevier
Sialic acids are cytoprotectors, mainly localized on the surface of cell membranes with
multiple and outstanding cell biological functions. The history of their structural analysis,
occurrence, and functions is fascinating and described in this review. Reports from different
researchers on apparently similar substances from a variety of biological materials led to the
identification of a 9-carbon monosaccharide, which in 1957 was designated “sialic acid.”
The most frequently occurring member of the sialic acid family is N-acetylneuraminic acid …
multiple and outstanding cell biological functions. The history of their structural analysis,
occurrence, and functions is fascinating and described in this review. Reports from different
researchers on apparently similar substances from a variety of biological materials led to the
identification of a 9-carbon monosaccharide, which in 1957 was designated “sialic acid.”
The most frequently occurring member of the sialic acid family is N-acetylneuraminic acid …