Sialic acids (Sias) are terminal components of many glycoproteins and glycolipids especially
of higher animals. In this exposed position they contribute significantly to the structural
properties of these molecules, both in solution and on cell surfaces. Therefore, it is not
surprising that Sias are important regulators of cellular and molecular interactions, in which
they play a dual role. They can either mask recognition sites or serve as recognition
determinants. Whereas the role of Sias in masking and in binding of pathogens to host cells …