Context Nitroglycerin stimulates bone formation and inhibits bone resorption, is inexpensive,
and is widely available. Its effects on bone density, bone structure, and bone strength are
unknown. Objectives To determine if nitroglycerin increases lumbar spine bone mineral
density (BMD) and to evaluate changes in hip BMD, bone geometry, and density at the
radius and tibia, and markers of bone turnover. Design, Setting, and Participants A single-
center, double-blind, placebo-controlled randomized trial conducted in Toronto, Ontario …