[HTML][HTML] Rapid detection of the “highly virulent” group B Streptococcus ST-17 clone
MC Lamy, S Dramsi, A Billoët, H Réglier-Poupet… - Microbes and …, 2006 - Elsevier
Group B streptococcus (GBS) is a leading cause of neonatal morbidity and mortality.
Multilocus sequence typing (MLST) revealed that the sequence type ST-17 defines a “highly
virulent” serotype III clone strongly associated with neonatal invasive infections. Our aim was
to identify a target sequence enabling rapid, simple, and specific detection of this clone by a
real-time PCR assay. Conventional methods for DNA manipulation and gene analyses were
used to characterize the gbs2018 gene variant specific for ST-17 clone and to design ST-17 …
Multilocus sequence typing (MLST) revealed that the sequence type ST-17 defines a “highly
virulent” serotype III clone strongly associated with neonatal invasive infections. Our aim was
to identify a target sequence enabling rapid, simple, and specific detection of this clone by a
real-time PCR assay. Conventional methods for DNA manipulation and gene analyses were
used to characterize the gbs2018 gene variant specific for ST-17 clone and to design ST-17 …