Abstract The Immunoglobulin G (IgG) glycome is well known for its heterogeneity and shows
a significant degree of variation within populations. IgG glycome composition is influenced
both by genes and by environment, making it an excellent biomarker of a person's general
health state, ie biological age. IgG glycosylation appears to be highly regulated, both during
homeostasis and in cases of its disturbance. Changes in IgG glycosylation patterns have
been observed in aging and in various diseases. Differential IgG glycosylation is known to …