Hyposialorrhea as an early manifestation of Parkinson disease
MG Cersósimo, OR Tumilasci, GB Raina… - Autonomic …, 2009 - Elsevier
We sought to determine whether hyposialorrhea is an early manifestation of Parkinson
disease (PD). We measured basal and citric acid stimulated secretion of whole saliva in 20
patients with early stage (Hoehn–Yahr I–II) PD who had motor symptoms for less than 1 year
and were on no medication and 11 age matched controls. Compared to controls, PD
patients had significant reduction of both basal (0.0964±0.08 vs 0.293±0.112 ml/min, p<
0.001) and reflex (0.263±0.213 vs 0.537±0.313 ml/min, p< 0.001) salivary secretion. Our …
disease (PD). We measured basal and citric acid stimulated secretion of whole saliva in 20
patients with early stage (Hoehn–Yahr I–II) PD who had motor symptoms for less than 1 year
and were on no medication and 11 age matched controls. Compared to controls, PD
patients had significant reduction of both basal (0.0964±0.08 vs 0.293±0.112 ml/min, p<
0.001) and reflex (0.263±0.213 vs 0.537±0.313 ml/min, p< 0.001) salivary secretion. Our …