Gastro-intestinal manifestations of porphyria
L Berlin, R Cotton - The American Journal of Digestive Diseases, 1950 - Springer
L Berlin, R Cotton
The American Journal of Digestive Diseases, 1950•SpringerSummary and Conclusions Abdominal pain is a prominent symptom in acute porphyria. This
may be attributed to the marked hypomotility and distention which is usually present in some
segment of the gastro-intestinal tract. The entire tract may at times be affected. A case is
presented which manifested pronounced atony of the esophagus, stomach, and colon.
These findings were evident roentgenologically in the conspicuous dilatation and the
prolonged retention of barium within these stractures. Occasionally diarrhea and spasm of …
may be attributed to the marked hypomotility and distention which is usually present in some
segment of the gastro-intestinal tract. The entire tract may at times be affected. A case is
presented which manifested pronounced atony of the esophagus, stomach, and colon.
These findings were evident roentgenologically in the conspicuous dilatation and the
prolonged retention of barium within these stractures. Occasionally diarrhea and spasm of …
Summary and Conclusions
Abdominal pain is a prominent symptom in acute porphyria. This may be attributed to the marked hypomotility and distention which is usually present in some segment of the gastro-intestinal tract. The entire tract may at times be affected. A case is presented which manifested pronounced atony of the esophagus, stomach, and colon. These findings were evident roentgenologically in the conspicuous dilatation and the prolonged retention of barium within these stractures.
Occasionally diarrhea and spasm of portions of the gastro-intestinal tract occur.
The disturbance of gastro-intestinal function is probably due to the toxic effect of the porphyrins upon the autonomic nerves.
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