Excess of adipose tissue is accompanied by an increase in the risk of developing insulin
resistance, type 2 diabetes (T2D) and other complications. Nevertheless, total or partial
absence of fat or its accumulation in other tissues (lipotoxicity) is also associated to these
complications. White adipose tissue (WAT) was traditionally considered a metabolically
active storage tissue for lipids while brown adipose tissue (BAT) was considered as a
thermogenic adipose tissue with higher oxidative capacity. Nowadays, WAT is also …