Decreased plasma adiponectin concentration in patients with essential hypertension
M Adamczak, A Wiȩcek, T Funahashi… - American journal of …, 2003 - academic.oup.com
M Adamczak, A Wiȩcek, T Funahashi, J Chudek, F Kokot, Y Matsuzawa
American journal of hypertension, 2003•academic.oup.comAdipocytes secrete several biologically active substances that are presumed to be involved
in obesity-related hypertension. There are no reports that deal with the relationship between
plasma adiponectin concentration and blood pressure (BP). To evaluate the role of
adiponectin in essential hypertension 33 patients with essential hypertensive (EHP)(12
women, 21 men) and 33 body mass index-matched normotensive healthy subjects
(NHS)(13 women, 20 men) were studied. In EHP plasma adiponectin concentration was …
in obesity-related hypertension. There are no reports that deal with the relationship between
plasma adiponectin concentration and blood pressure (BP). To evaluate the role of
adiponectin in essential hypertension 33 patients with essential hypertensive (EHP)(12
women, 21 men) and 33 body mass index-matched normotensive healthy subjects
(NHS)(13 women, 20 men) were studied. In EHP plasma adiponectin concentration was …
Abstract
Adipocytes secrete several biologically active substances that are presumed to be involved in obesity-related hypertension. There are no reports that deal with the relationship between plasma adiponectin concentration and blood pressure (BP).
To evaluate the role of adiponectin in essential hypertension 33 patients with essential hypertensive (EHP) (12 women, 21 men) and 33 body mass index-matched normotensive healthy subjects (NHS) (13 women, 20 men) were studied.
In EHP plasma adiponectin concentration was significantly lower than in NHS (9.1 ± 4.5 v 13.7 ± 5.2 μg/mL, respectively). In all subjects a significant negative correlation was found between plasma adiponectin concentration and mean, systolic, and diastolic BP, suggesting that adiponectin contributes to the clinical course of essential hypertension. Am J Hypertens 2003;16:72–75 @ 2003 American Journal of Hypertension, Ltd.
Oxford University Press