Predictors of acquired lipodystrophy in juvenile-onset dermatomyositis and a gradient of severity
A Bingham, G Mamyrova, KI Rother, E Oral, E Cochran… - Medicine, 2008 - journals.lww.com
We describe the clinical features of 28 patients with juvenile dermatomyositis (JDM) and 1
patient with adult-onset dermatomyositis (DM), all of whom developed lipodystrophy (LD)
that could be categorized into 1 of 3 phenotypes, generalized, partial, or focal, based on the
pattern of fat loss distribution. LD onset was often delayed, beginning a median of 4.6 years
after diagnosis of DM. Calcinosis, muscle atrophy, joint contractures, and facial rash were
DM disease features found to be associated with LD. Panniculitis was associated with focal …
patient with adult-onset dermatomyositis (DM), all of whom developed lipodystrophy (LD)
that could be categorized into 1 of 3 phenotypes, generalized, partial, or focal, based on the
pattern of fat loss distribution. LD onset was often delayed, beginning a median of 4.6 years
after diagnosis of DM. Calcinosis, muscle atrophy, joint contractures, and facial rash were
DM disease features found to be associated with LD. Panniculitis was associated with focal …