• We observed three children with a clinically similar presentation of erythematous nodules
that expanded centrifugally leaving lipoatrophy. Areas of lipoatrophy coalesced, resulting in
clinical pictures similar to partial or total lipodystrophy. Histologic study revealed a lobular
panniculitis with a mixed infiltrate of lymphocytes and mononuclear phagocytes. Of these
three children, one had insulin-dependent diabetes mellitus and Hashimoto's thyroiditis, one
developed juvenile rheumatoid arthritis, and the third developed insulin-dependent diabetes …