Cyclin a correlates with carcinogenesis and metastasis, and p27kip1 correlates with lymphatic invasion, in colorectal neoplasms
JQ Li, H Miki, F Wu, K Saoo, M Nishioka, M Ohmori… - Human pathology, 2002 - Elsevier
Cyclin A binds to CDK2 and plays critical roles when cells proliferate; staining for Ki67 can
monitor the proliferation. The cyclin A expression pattern remains unclear in colorectal
carcinogenesis and remote metastasis, however, and no one has reported on the
association of its expression with key clinicopathologic factors in primary cancer. p27kip1
protein [mdash] an extremely important inhibitor of CDK2 [mdash] seems unchanged as
colorectal cancers metastasize to the lymph nodes, a result contrary to that seen in gastric …
monitor the proliferation. The cyclin A expression pattern remains unclear in colorectal
carcinogenesis and remote metastasis, however, and no one has reported on the
association of its expression with key clinicopathologic factors in primary cancer. p27kip1
protein [mdash] an extremely important inhibitor of CDK2 [mdash] seems unchanged as
colorectal cancers metastasize to the lymph nodes, a result contrary to that seen in gastric …