[HTML][HTML] Devilishly radical NETwork in COVID-19: Oxidative stress, neutrophil extracellular traps (NETs), and T cell suppression
G Schönrich, MJ Raftery, Y Samstag - Advances in biological regulation, 2020 - Elsevier
Abstract Pandemic coronavirus disease 2019 (COVID-19) is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge
to healthcare systems due to the lack of a vaccine and specific treatment options.
Accordingly, there is an urgent need to understand precisely the pathogenic mechanisms
underlying this multifaceted disease. There is increasing evidence that the immune system
reacts insufficiently to SARS-CoV-2 and thus contributes to organ damage and to lethality. In …
respiratory syndrome coronavirus 2 (SARS-CoV-2) and poses an unprecedented challenge
to healthcare systems due to the lack of a vaccine and specific treatment options.
Accordingly, there is an urgent need to understand precisely the pathogenic mechanisms
underlying this multifaceted disease. There is increasing evidence that the immune system
reacts insufficiently to SARS-CoV-2 and thus contributes to organ damage and to lethality. In …