High availability of NO, oxidative stress and neutrophil extracellular trap (NETs) contents are
often noticed at the site of inflammation/infection. Studies from this lab and others have
reported NO mediated free radical generation from neutrophils; role of NO in NETs formation
however remains undefined so far. The present study was therefore undertaken to explore
the effect of NO donors on NET release from human neutrophils (PMNs), using
confocal/scanning microscopy, measuring the extracellular DNA content and NET-bound …