Retention in the circulation of dextrose in normal and depancreatized animals, and the effect of an intravenous injection of an emulsion of pancreas upon this retention

IS Kleiner, SJ Meltzer - … of the National Academy of Sciences, 1915 - National Acad Sciences
IS Kleiner, SJ Meltzer
Proceedings of the National Academy of Sciences, 1915National Acad Sciences
rapidly from the circulation. Ninety minutes after the infusion, the dextrose content of the
blood reached nearly the same level which it had before the injection. About one-half of the
injected quantity of dextrose left the circulation through the kidneys; the other half went into
the tissues. In nephrectomized animals also the dextrose returned to the previouslevel in the
same length of time. Here we have a strikingexample of the ability and readiness of the
circulation of a normal animal to rid itself ofa large surplus ofdextrose.
rapidly from the circulation. Ninety minutes after the infusion, the dextrose content of the blood reached nearly the same level which it had before the injection. About one-half of the injected quantity of dextrose left the circulation through the kidneys; the other half went into the tissues. In nephrectomized animals also the dextrose returned to the previouslevel in the same length of time. Here we have a strikingexample of the ability and readiness of the circulation of a normal animal to rid itself ofa large surplus ofdextrose.
National Acad Sciences