Importance Atrial fibrillation (AF) is the most common rhythm disorder seen in clinical
practice. Antiarrhythmic drugs are effective for reduction of recurrence in patients with
symptomatic paroxysmal AF. Radiofrequency ablation is an accepted therapy in patients for
whom antiarrhythmic drugs have failed; however, its role as a first-line therapy needs further
investigation. Objective To compare radiofrequency ablation with antiarrhythmic drugs
(standard therapy) in treating patients with paroxysmal AF as a first-line therapy. Design …