[HTML][HTML] Intramuscular fat and inflammation differ in older adults: the impact of frailty and inactivity

O Addison, MJ Drummond, PC LaStayo… - The Journal of nutrition …, 2014 - Elsevier
Objectives Intramuscular adipose tissue (IMAT) is recognized as a negative predictor of both
muscle and mobility function in older adults, however the mechanism by which IMAT may
negatively influence muscle and mobility function is currently unknown. The release of pro-
inflammatory cytokines from IMAT provides a potential reason for these negative
associations. To explore this hypothesis we compared IMAT and muscular inflammation in
age-and BMI-matched older non-obese frail and non-frail adults. We also sought to examine …