The importance of hypoxia and extra physiologic oxygen shock/stress for collection and processing of stem and progenitor cells to understand true physiology …
Current opinion in hematology, 2015•journals.lww.com
Our recent findings may be advantageous for HSC collection for hematopoietic cell
transplantation, and likely for enhanced collection of other stem cell types. EPHOSS should
be considered when ex-vivo cell analysis is utilized for personalized medicine, as
metabolism of cells and their response to targeted drug treatment ex vivo may not mimic
what occurs in vivo.
transplantation, and likely for enhanced collection of other stem cell types. EPHOSS should
be considered when ex-vivo cell analysis is utilized for personalized medicine, as
metabolism of cells and their response to targeted drug treatment ex vivo may not mimic
what occurs in vivo.
Summary
Our recent findings may be advantageous for HSC collection for hematopoietic cell transplantation, and likely for enhanced collection of other stem cell types. EPHOSS should be considered when ex-vivo cell analysis is utilized for personalized medicine, as metabolism of cells and their response to targeted drug treatment ex vivo may not mimic what occurs in vivo.
Lippincott Williams & Wilkins