[HTML][HTML] The pathology and pathogenesis of experimental severe acute respiratory syndrome and influenza in animal models
JMA Van den Brand, BL Haagmans, D van Riel… - Journal of comparative …, 2014 - Elsevier
Respiratory viruses that emerge in the human population may cause high morbidity and
mortality, as well as concern about pandemic spread. Examples are severe acute respiratory
syndrome coronavirus (SARS-CoV) and novel variants of influenza A virus, such as H5N1
and pandemic H1N1. Different animal models are used to develop therapeutic and
preventive measures against such viruses, but it is not clear which are most suitable.
Therefore, this review compares animal models of SARS and influenza, with an emphasis …
mortality, as well as concern about pandemic spread. Examples are severe acute respiratory
syndrome coronavirus (SARS-CoV) and novel variants of influenza A virus, such as H5N1
and pandemic H1N1. Different animal models are used to develop therapeutic and
preventive measures against such viruses, but it is not clear which are most suitable.
Therefore, this review compares animal models of SARS and influenza, with an emphasis …