Cytogenetic analysis of ten human seminomas

SMMJ Castedo, B de Jong, JW Oosterhuis, R Seruca… - Cancer research, 1989 - AACR
SMMJ Castedo, B de Jong, JW Oosterhuis, R Seruca, GJ te Meerman, A Dam, HS Koops
Cancer research, 1989AACR
A cytogenetic analysis of ten seminomas has been carried out after direct harvesting of the
tumor cells. Modal chromosome numbers ranged from 63 to 112. These numbers were in
agreement with flow cytometric determination of the DNA content of the tumors. Eight tumors
had at least one copy of an i (12p) among other chromosomal abnormalities. Two
seminomas lacked the i (12p).
Abstract
A cytogenetic analysis of ten seminomas has been carried out after direct harvesting of the tumor cells. Modal chromosome numbers ranged from 63 to 112. These numbers were in agreement with flow cytometric determination of the DNA content of the tumors. Eight tumors had at least one copy of an i(12p) among other chromosomal abnormalities. Two seminomas lacked the i(12p).
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