Association between mediastinal germ cell tumors and hematologic malignancies: report of two cases and review of the literature
SH DeMent, JC Eggleston… - The American journal of …, 1985 - journals.lww.com
A hematologic malignancy occurred simultaneously with a malignant mediastinal germ cell
tumor in two men. In one instance the blood disorder was acute nonlymphocytic leukemia,
and in the other, malignant histiocytosis. We subsequently identified nine additional patients,
all male (age range 12-48 years), with a mediastinal germ cell tumor and either acute
nonlymphocytic leukemia or malignant histiocytosis. Six of the 11 patients had not received
either radiation or chemotherapy before development of the hematologic malignancy. One …
tumor in two men. In one instance the blood disorder was acute nonlymphocytic leukemia,
and in the other, malignant histiocytosis. We subsequently identified nine additional patients,
all male (age range 12-48 years), with a mediastinal germ cell tumor and either acute
nonlymphocytic leukemia or malignant histiocytosis. Six of the 11 patients had not received
either radiation or chemotherapy before development of the hematologic malignancy. One …