[HTML][HTML] Regulation of the transcriptional activity of the IRF7 promoter by a pathway independent of interferon signaling
S Ning, LE Huye, JS Pagano - Journal of Biological Chemistry, 2005 - ASBMB
Genes containing an interferon (IFN)-stimulated response element (ISRE) can be divided
into two groups according to their inducibility by IFN and virus infection: one induced only by
IFN and the other induced by both IFN and virus infection. Although it is now clear that IFN
regulatory factor 7 (IRF7) is a multifunctional gene essential for induction of type I IFNs,
regulation of the IRF7 promoter (IRF7p) is poorly understood. The IRF7 gene includes two
IFN responsive elements, an IRF-binding element (IRFE) in the promoter region and an …
into two groups according to their inducibility by IFN and virus infection: one induced only by
IFN and the other induced by both IFN and virus infection. Although it is now clear that IFN
regulatory factor 7 (IRF7) is a multifunctional gene essential for induction of type I IFNs,
regulation of the IRF7 promoter (IRF7p) is poorly understood. The IRF7 gene includes two
IFN responsive elements, an IRF-binding element (IRFE) in the promoter region and an …