[HTML][HTML] Dexamethasone in hospitalized patients with Covid-19

RECOVERY Collaborative Group - New England Journal of …, 2021 - Mass Medical Soc
Abstract Background Coronavirus disease 2019 (Covid-19) is associated with diffuse lung
damage. Glucocorticoids may modulate inflammation-mediated lung injury and thereby
reduce progression to respiratory failure and death. Methods In this controlled, open-label
trial comparing a range of possible treatments in patients who were hospitalized with Covid-
19, we randomly assigned patients to receive oral or intravenous dexamethasone (at a dose
of 6 mg once daily) for up to 10 days or to receive usual care alone. The primary outcome …

Effect of dexamethasone in hospitalized patients with COVID-19–preliminary report

P Horby, WS Lim, J Emberson, M Mafham, J Bell… - MedRxiv, 2020 - medrxiv.org
ABSTRACT Background Coronavirus disease 2019 (COVID-19) is associated with diffuse
lung damage. Corticosteroids may modulate immune-mediated lung injury and reducing
progression to respiratory failure and death. Methods The Randomised Evaluation of COVID-
19 therapy (RECOVERY) trial is a randomized, controlled, open-label, adaptive, platform
trial comparing a range of possible treatments with usual care in patients hospitalized with
COVID-19. We report the preliminary results for the comparison of dexamethasone 6 mg …