Different laboratory animal models of neuropathic pain that replicate pathophysiological
changes in patients have been developed. In most animal models of neuropathic pain, both
sensory and motor nerves are injured. Thus, animals usually show both abnormal sensory
and motor responses. Assessment of the sensory system is likely to be affected by the motor
defects, although motor functions have not been evaluated in previous neuropathic pain
models. An ideal neuropathic pain model to assess behavioral nociceptive responses in …