Atorvastatin for lowering lipids

SP Adams, M Tsang, JM Wright - Cochrane Database of …, 2015 - cochranelibrary.com
Cochrane Database of Systematic Reviews, 2015cochranelibrary.com
Background This represents the first update of this review, which was published in 2012.
Atorvastatin is one of the most widely prescribed drugs and the most widely prescribed statin
in the world. It is therefore important to know the dose‐related magnitude of effect of
atorvastatin on blood lipids. Objectives Primary objective To quantify the effects of various
doses of atorvastatin on serum total cholesterol, low‐density lipoprotein (LDL)‐cholesterol,
high‐density lipoprotein (HDL)‐cholesterol and triglycerides in individuals with and without …
Background
This represents the first update of this review, which was published in 2012. Atorvastatin is one of the most widely prescribed drugs and the most widely prescribed statin in the world. It is therefore important to know the dose‐related magnitude of effect of atorvastatin on blood lipids.
Objectives
Primary objective
To quantify the effects of various doses of atorvastatin on serum total cholesterol, low‐density lipoprotein (LDL)‐cholesterol, high‐density lipoprotein (HDL)‐cholesterol and triglycerides in individuals with and without evidence of cardiovascular disease. The primary focus of this review was determination of the mean per cent change from baseline of LDL‐cholesterol.
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