[HTML][HTML] Neuropsychiatric disease–associated genetic variants of the dopamine transporter display heterogeneous molecular phenotypes
Genetic factors are known to significantly contribute to the etiology of psychiatric diseases
such as attention deficit hyperactivity disorder (ADHD) and autism spectrum and bipolar
disorders, but the underlying molecular processes remain largely elusive. The dopamine
transporter (DAT) has received continuous attention as a potential risk factor for psychiatric
disease, as it is critical for dopamine homeostasis and serves as principal target for ADHD
medications. Constrain metrics for the DAT-encoding gene, solute carrier family 6 member 3 …
such as attention deficit hyperactivity disorder (ADHD) and autism spectrum and bipolar
disorders, but the underlying molecular processes remain largely elusive. The dopamine
transporter (DAT) has received continuous attention as a potential risk factor for psychiatric
disease, as it is critical for dopamine homeostasis and serves as principal target for ADHD
medications. Constrain metrics for the DAT-encoding gene, solute carrier family 6 member 3 …