The expression of neuropilin-1 in human placentas from normal and preeclamptic pregnancies
A Arad, S Nammouz, Y Nov, G Ohel… - International Journal …, 2017 - journals.lww.com
Preeclampsia (PET) is a hypertensive disorder that affects 2% to 8% of pregnant women.
Recent observations support the hypothesis that upregulation of placental anti-angiogenic
factors are responsible for the clinical manifestations of the disease. Neuropilin-1 (NP-1) is a
transmembrane protein that acts as a coreceptor for vascular endothelial growth factor and
as a regulatory protein in the immune system. The aim of the study was to evaluate the
expression of NP-1 in PET and normal placentas. Nineteen placental specimens from …
Recent observations support the hypothesis that upregulation of placental anti-angiogenic
factors are responsible for the clinical manifestations of the disease. Neuropilin-1 (NP-1) is a
transmembrane protein that acts as a coreceptor for vascular endothelial growth factor and
as a regulatory protein in the immune system. The aim of the study was to evaluate the
expression of NP-1 in PET and normal placentas. Nineteen placental specimens from …